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SHBG concentrations are increased in pregnancy, hyperthyroidism, cirrhosis, oral estrogen administration and by certain drugs. Concentrations are decreased by testosterone, hypothyroidism, Cushings syndrome, acromegaly and obesity.
Best taken between weeks 35 and 37 of pregnancy, this enriched culture medium swab profile consists of 2 swabs - one vaginal and the other rectal. Knowing the mother's GBS status can increase survival rates of newborns.
For a more accurate Testosterone assessment free testosterone will often be included as it is possible to have a normal total testosterone level without it being free in the bloodstream and available to the body.